What is a cholesterol-lowering drug?

Lipid-lowering drugs are drugs used to treat patients with abnormal blood lipid levels or Dyslipidemia, which is caused by an imbalance of various types of fat in the bloodstream, including cholesterol, triglycerides, bad cholesterol (LDL), and good cholesterol (HDL). Having abnormal blood lipid levels that cannot be controlled and are not treated can lead to cardiovascular disease that causes severe complications, such as clogged arteries or cerebrovascular disease. Therefore, using lipid-lowering drugs will help treat abnormal blood lipid levels and reduce the risk of cardiovascular disease that may occur in the future.

What symptoms should be treated with lipid-lowering drugs?

According to the 2019 ESC/EAS Guidelines for the treatment of dyslipidemia, it is recommended that patients with LDL or bad cholesterol levels of 190 mg/dL or higher who are unable to control their blood lipid levels by changing their behavior https://ufabet999.app should receive lipid-lowering medication. In addition, in patients with LDL in the blood exceeding 190 mg/dL or patients whom the doctor has determined to be at high risk of developing cardiovascular disease, the doctor will consider starting lipid-lowering medication on the patient.

Types of lipid-lowering drugs

1. Statins

Statins, also known as “cholesterol-lowering drugs,” work by inhibiting an enzyme that helps the body synthesize cholesterol. When cholesterol is lowered, the body’s levels of bad cholesterol (LDL) and triglycerides in the bloodstream are also lower. Examples of statins include: 

• Simvastatin drugs such as Bestatin , Zimmex , Zimva ,
• Rosuvastatin drugs such as Crestatin , Otagil , Rovas , Vivacor ,
• Atorvastatin drugs such as Xarator , Chlovas , Atorsan , Atorvin
• Pitavastatin drugs such as Pitasor
• Pravastatin drugs such as Mevalotin
• Fluvastatin drugs such as Lescol XL

3. Resins

Resin drugs or bile acid sequestrants work by reducing fat by binding to bile in the digestive tract, preventing its reabsorption into the bloodstream. As a result, the liver stimulates the liver to draw more cholesterol into liver cells. The cholesterol and LDL levels in the bloodstream can therefore be reduced. Examples of resin drugs include: 

• Cholestyramine
• Cholestyramine

4. Ezetimibe group of drugs

Ezetimibe works by reducing the levels of bad (LDL) cholesterol in the blood by inhibiting its absorption in the intestines. This lipid-lowering drug is often used in combination with a statin. Examples of drugs that contain ezetimibe include Ezetrol , Ezentia , Mibeaz , Co-Ezetimibe TEVA , Atozet ®, Vytirin .

5. Niacin group drugs

Niacinamide, or niacin, is a high-dose derivative of vitamin B3 that works by inhibiting the action of enzymes in the liver and fatty tissue. It helps reduce levels of bad cholesterol (LDL) and increase levels of good cholesterol (HDL) in the blood. Examples of drugs in this group include Niaspan .